Best 50/50 Vape Juice: My #1 Picks For 2022…

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Looking for amazing 50/50 vape juice for your pod or MTL tank? I was too, so I tested hundreds of them to find the best 50/50 vape juice on the market… 


50/50 vape juice is designed for use in MTL tanks – tanks like a Kayfun Mini, for instance – and pod vapes like the UWELL Caliburn A2. You would not want to use 50/50 vape juice in a sub-ohm tank, it’d be too harsh. But in an MTL or pod vape, it is perfect, especially if you don’t want to use Nic Salts juice. 

But what are the best 50/50 vape juice brands to look out for in 2022 and beyond? Here’s my guide to the best brands and flavors I have personally tested during the past 18 months. In no particular order… 

Best 50/50 Vape Juice Brands 

What is 50/50 Vape Juice?

Vape juice – or e liquid or e juice, as it is sometimes known – comes in a few different kinds. And the reason for this is that different types of vape juice are used in different types of vape devices.

50/50 refers to the mix of propylene glycol and vegetable glycerin. In the context of 50/50 vape juice, you have a mix of 50% of each, hence the name.

Propylene glycol, or PG, is what gives vape juice its flavor and throat-hit; the higher the PG, the harsher the vape juice tastes. I say, harsh, but what I really mean is throat hit.

If you have 50/50 vape juice, where 50% of the liquid is made up of propylene glycol, you’ll get a nice throat hit and plenty of flavor.

This is why 50/50 vape juice is used in pod vapes and MTL tanks.

With vegetable glycerin, this is where you get the smoothness. This is why sub ohm tanks, the type that produces massive amounts of vapor, use high vegetable glycerin (VG) blends of vape juice.

You DO NOT want a throat-hit with a sub ohm tank; it’d make you cough your guts up. This is why all vape juice designed for sub ohm vaping is usually 80% to 100% vegetable glycerin (VG).

Here’s a handy table that shows you what type of tank you should be using with your mix of vape juice.


Vape Juice MixType of VapePower Output
50/50 Vape JuiceMTL Tanks, Pods & MTL Vape PensLower Than 20W
80% VG RDAs, Mesh Tanks, RTAs, Sub-Ohm Pods50W to 100W

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